Achillea millefolium L. (Asteraceae), popularly known as yarrow, has been used in traditional medicine to treat complaints such as gastrointestinal disturbances, hemorrhages, wounds, inflammation and pain. The aim of the present study was to assess the analgesic effects of aqueous extract of Achillea millefolium L. (AE) in the rat’s formalin test. Oral administration of different doses of AE (8...

Interleukin-1β (IL-1β) has a role in β- cell destruction in autoimmune diabetes by stimulating the expression of inducible nitric oxide synthase (iNOS) that generates the free radical nitric oxide. We aimed to investigate the effect of Achillea millefolium L, as a traditional hypoglycemic agent, on IL-1β and iNOS gene expression of pancreatic tissue in the STZ- induced diabetic rats. Forty adul...

Achillea millefolium and Achillea ptarmica are both plants belonging to the Asteracea family and are traditionally used for their medicinal properties. It has already been shown that some N-alkylamides (NAAs) are responsible for these pharmacological actions. Therefore, in the present study, the NAA content of the two plants was analytically characterised. Different extracts were prepared from ...

Mathematical, fuzzy logic and artificial neural network modeling of extraction kinetics essential oil from aerial parts yarrow (Achillea millefolium L.) using ohmic-assisted hydrodistillation

In this study, a new chromosome number for Iranian yarrow (Achillea millefolium L.) accessions was reported. Cytological analyses on four Achillea millefolium accessions, indicated that two accessions were diploids (2n=2x=18) and two tetraploids (2n=4x=36). Cluster analysis based on chromosomal characteristics and karyotype asymmetry, categorized the four accessions separated into two groups. I...

The Achillea millefolium L. (Yarrow) is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attri...

Achillea millefolium Linn. (Asteraceae) is used in folk medicine for the treatment of overactive cardiovascular and respiratory ailments. This study describes its hypotensive, cardio-depressant, vasodilatory and bronchodilatory activities. The crude extract of Achillea millefolium (Am.Cr) caused a dose-dependent (1-100 mg/kg) fall in arterial blood pressure of rats under anaesthesia. In spontan...

BACKGROUND & OBJECTIVES Leishmaniasis is a parasitic disease transmitted by sand flies. Many investigations are performed to find an effective and safe treatment for leishmaniasis. In this study, we evaluated the efficacy of herbal extracts of Thymus vulgaris (Thyme) and Achillea millefolium (Yarrow), propolis hydroalcoholic extract and systemic glucantime against cutaneous leishmaniasis in Bal...

Nowadays, medicinal plants used in folk medicine are being increasingly studied and used on pharmaceutical, food and nutraceutical fields. Yarrow (Achillea millefolium L.) is widely used in both folk and official medicine. Therefore, in the present paper different extracts of yarrow inflorescences and upper leaves were investigated for their total polyphenolic content and antioxidant activity u...

Throughout many years of studying mycopopulation of weeds, we have found fungi of the Diaporthe/ Phomopsis complex interesting to research. After years of examining plants of Achillea millefolium L., some of them exhibited symptoms of infection typical for Diaporthe/Phomopsis species. A. millefolium was usually found in uncultivated, pasture and forest flora, but also in or nearby sunflower fie...